The erythroid component consists predominantly or exclusively of proerythroblasts and early basophilic erythroblasts.
2.
Precursors of red cells, the proerythroblasts and basophilic erythroblasts also express erythropoietin receptor and are therefore affected by it.
3.
Most of the expression is in the proerythroblast ( P ) stage, and a minor amount in the basophilic erythroblast ( B ) stage.
4.
In this form of AML, levels of erythroblasts can reach up to 94.8 % of all nucleated cells in the bone marrow, and the immature forms of the erythroblasts, the proerythroblasts and basophilic erythroblasts, are more commonly found.
5.
Early erythroid progenitors are found at a quite low frequency relative to later stages of erythroid differentiation, such as the pro-erythroblast and the basophilic erythroblast stages which can be detected by flowcytometry directly ex-vivo ( Socolovsky et al . 2001 PMID 11719363 ).
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